Methylation Markers Distinguish Aggressive from Manageable Prostate Cancer

Scientists in the U.K. and Canada have identified a DNA methylation signature that they claim can distinguish aggressive prostate cancer from more manageable disease, with up to 92% accuracy. The researchers, headed by Norman Maitland, Ph.D., at the University of York’s department of biology, hope that the pattern of 17 epigenetic markers could be used to assess each case of prostate cancer before deciding on whether the patient will need to undergo surgery or radiotherapy, or whether they