Low-Fat and Reduced-Calorie Diet May Prevent Age-Related Brain Changes

Scientists report that a low-fat diet in combination with limited caloric consumption prevents activation of the brain's microglia in aging mice. The study (“ Low-Fat Diet With Caloric Restriction Reduces White Matter Microglia Activation During Aging ”), published in Frontiers in Molecular Neuroscience , also finds that exercise is significantly less effective than caloric restriction in preventing these age-related changes.“Rodent models of both aging and obesity ar