Llama-Derived Nanobody May Tread Narrow Anticancer Path

Along the upper reaches of cell signaling loom the G protein-coupled receptors (GPCRs). From these serpentine structures descend pathways that diverge toward varied signaling outcomes, not all of which are desirable. For example, signaling cascades triggered by small-molecule drugs may lead to several types of cancer, neurological disorders, and drug addiction. Yet where small-molecule drugs may slip up, a sure-footed nanobody may stick to the right path, advancing targeted therapies.The nanobod