Leukemia Cells Take the Fast Track to the Nervous System

Scientists have uncovered how acute lymphoblastic leukemia (ALL) cells invade the central nervous system (CNS), a relatively common occurrence that makes the cancer immeasurably more difficult to treat. Despite being a characteristic across ALL subtypes, the mechanism of how the CNS invasion occurs remains unknown. The researchers used three different mouse models of ALL to study how human leukemia cells spread into the CNS. It has long been thought that these cells enter the CNS