Knockout Gene Model Has a Nose for Knockout Breath

Halitosis, or chronic bad breath, afflicts both mice and men, and mice may be used to model human halitosis. But scientists don’t have to put their noses up to mice’s mouths. Just ask the scientists who participated in an international effort to study halitosis at the genetic level. By studying patients from families afflicted with bad breath, and evaluating mice in which a suspect gene was “knocked out,” or disabled, the scientists identified a potentially frequent inbor