Immunological Memory Dependent Upon Single Transcription Factor

Immune cell memory is a critical line of defense for the body against repeat infections. Yet, for all their importance, the origins of memory T cells have remained a mystery. Now, investigators from The Scripps Research Institute's Florida campus may have just uncovered the origins of immune cell memory as they found a transcription factor protein called Runx3 puts dividing T cells on track to becoming memory T cells. Findings from the new study—published recently in Immunity through an ar