Immune Policing Surges with Decrease in Metalloproteinase Activity

Investigators at the Spanish National Center for Cardiovascular Research (CNIC)—studying the role of matrix metalloproteinases (MMPs) in the recruitment of immune cells and development of atherosclerosis—have just identified a novel function of an MMP that could be exploited for the treatment of some infections and even tumor metastasis. The new study—published today in Nature Communications in an article entitled “ MT4-MMP Deficiency Increases Patrolling Monocyte Recruit