Immune Cell Behavior May, Ironically, Suppress Effectiveness of Immunotherapy
Scientists say a process in an important immune cell may shed light on the limitations of immunotherapy as a cancer therapy.Regulatory T cells (Treg cells) are known to suppress immune function after T cells finish their job in fighting an infection. Cancer immunotherapy functions by boosting the immune system to attack cancer. Thus, when Tregs suppress the immune response, the cancer-fighting effect stops.Removing Tregs didn’t help reverse the situation as a clinical trial
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