Human Brain Organoids Thrive in Mouse Brains

Brain organoids, stem-cell-based models of real brain tissue, have moved into petri dishes and test tubes, but they have never quite felt themselves at home. The organoids’ cells don’t divide or diversify very much, and they don’t live very long, limiting their potential to recapitulate neurological diseases for the benefit of medical researchers and drug developers. Organoids may thrive, however, if they settle in more physiological environs—blood-vessel-rich regions of