HIV Drug Reduces Neurodegenerative Disease Pathology in Fruit Flies

Scientists at the University of Texas Health San Antonio have linked unwanted activation of transposable elements, or jumping genes, with nerve cell death in neurodegenerative tauopathies such as Alzheimer’s disease.  Their studies in fruit flies found that toxic tau protein deposition that is characteristic of tauopathies is associated with the disruption of epigenetic mechanisms that control the expression of transposable genetic elements, and that this dysregulation links with the