Genomic Wallflowers Join in Cell Identity Dance

Keeping to the margins of the nucleus, many genes seem to be left out of the cell development dance. These genes, like wallflowers at the prom, might even appear to be physically tethered. In fact, according to a new study, they are physically tethered—but not always. There are times when the tethers are released and seemingly shy genes are drawn into the whirl of activity that drives cell differentiation. These genes may even alter the choreography within stem cells that determines whethe