Gene Copies Amplify Pancreatic Cancer’s Aggressiveness

In a cancer as aggressive as pancreatic cancer, the roots of malignancy presumably run deep. Yet these roots are hard to trace. Nonetheless, persistent digging by scientists based at the Technical University of Munich (TUM) has uncovered mutational events that occur early in pancreatic cancer and explain how it eventually comes to grow and spread so quickly.The TUM team, led by Prof. Dr. Roland Rad and Prof. Dr. Dieter Saur, identified specific gene amplifications that occur along various evolut