For Some Chaperones, Stability Comes in Pairs

Chaperone molecules are an important part of protein dynamics for daily cellular function. Misfolded proteins are nonfunctional and can cause cell damage. To prevent this, cells have evolved an arsenal of chaperones that assist with folding and carry out protein quality control. Just like an acrobatic duo, some proteins lend each other stability, which is exactly what researchers at the Biozentrum of the University of Basel have discovered happens for a specific Escherichia coli chaperone called