For Malaria Vaccines to Improve, They’ll Need to Get Sweeter

The importance of glycosylation for protein drugs and vaccines has been well established, as companies spend millions of dollars either isolating or creating the appropriate glycosylated form of their desired compound—for increasing efficacy and extend the half-life of the drug. Yet, for the malaria parasite Plasmodium falciparum , researchers have often discounted carbohydrate moieties, since the parasite lacks much of the machinery to create the complex glycosylation patterns similar to