Fat Cells Inactivate Cancer Chemotherapy

Obesity is linked with poorer outcomes for patients with a range of cancers, including breast, colon, ovarian and prostate. The results from new studies now indicate that fat cells in a tumor microenvironment (TME) can directly take up and metabolize at least one type of chemotherapy, and so prevent the active drug  from reaching and killing the cancer cells."The finding that human fat cells can metabolize and inactivate a chemotherapy is novel and surprising," says the study’s lead s