Engineered Gut Bacteria Provide Enzyme That Aids Green Vegetables in Fighting Cancer

Scientists in Singapore have developed engineered probiotic gut bacteria that can transform a substance found naturally in broccoli and Brussels sprouts into a powerful cancer-preventing chemical. The National University of Singapore (NUS) team, led by Chun-Loong Ho, Ph.D., and associate professor Matthew Chang, Ph.D., engineered the harmless gut bacterium to attach specifically to the surface of colorectal cancer (CRC) cells and secrete an enzyme that converts the glucosinolate compounds in cru