DNA Origami Creates the World's Smallest Mona Lisa

Scientists at the California Institute of Technology (Caltech) have created what is possibly the world’s smallest Mona Lisa, using a mosaic of individual tiles of folded strands of DNA that, when viewed under atomic force microscopy (AFM), appears unmistakably as the enigmatic face of Leonardo da Vinci’s famous painting. The technique, developed by researchers in the laboratory of assistant professor of bioengineering Lulu Qian, Ph.D., builds on the original DNA origami technology de