CRISPR Defense Thwarted through Viral Cooperation

Gene editing using the CRISPR-Cas system has exploded with therapeutic potential over the last several years, and while researchers have begun to exploit the bacterial defense system to treat an array of diseases, little is known about the molecular battle between CRISPRs and invading viruses. A better understanding of these molecular events could enable therapeutic intervention using phage viruses. Now, two papers publishing simultaneously in Cell by researchers from independent groups provide