Cancer-Linked Rearrangements Pepper Genome’s Regulatory Regions

When cancer is studied at the genomic level, certain variations tend to receive a lot of attention, chiefly the variations affecting protein-coding genes, which include variations such as point mutations and copy number alterations. Yet variations that affect non-protein–coding parts of the genome matter, too. But how much do they matter?The question has persisted, even while genomic information has been piling up in data repositories. Now, by sifting through some of this information, scie