Cancer Chemotherapy Resistance Stopped By Chromatin Regulation

Researchers at Northwestern University have developed a new approach to treating cancer that effectively changes the physical structure of chromatin and blocks the cell’s ability to modify global gene expression patterns and evolve resistance to therapy.The researchers, led by Vadim Backman, Ph.D., the Walter Dill Scott Professor of Biomedical Engineering at Northwestern's McCormick School of Engineering, tested the macrogenomics engineering approach using two immunologic drugs that are ma