Autophagy Study Suggests New Strategy for Treating Age-Related Neurodegenerative Diseases

Scientists from Brown University say they have demonstrated a novel method for stimulating autophagy. In a study (“ Nuclear Export Inhibition Enhances HLH-30/TFEB Activity, Autophagy, and Lifespan ”), published in  Cell Reports , the team shows that the approach increased the lifespans of worms and flies, and experiments in human cells hint that the strategy could be useful in future treatments for Alzheimer's disease, amyotrophic lateral sclerosis ( ALS), and oth