Antibody Offers New Approach to Treating Inflammatory Diseases

Scientists at the University of California San Diego School of Medicine discovered that they can block inflammation in mice with a naturally occurring antibody that binds oxidized phospholipids (OxPL) molecules on cell surfaces that get modified by inflammation. Even while on a high-fat diet, the antibody protected the mice from arterial plaque formation, hardening of the arteries and liver disease, and prolonged their lives.The study (“ Oxidized phospholipids are proinflammatory and proat