Altering Tumor Microenvironment May Offer New Approach to Metastatic Melanoma Therapy

Researchers at the Wistar Institute and the Medical University of Vienna say they have identified the role of tumor-infiltrating or tumor-associated B-cells (TABs) in melanoma progression and resistance to targeted therapy. A molecular mechanism that governs the interactions between TABs and tumor cells has now been clarified and this could lead to a potential new therapeutic strategy for combating tumors resistant to treatment, according to the scientists.Their study (Tumor-associated B-cells i