Algorithm Devised for Reprogramming One Type of Cell into Any Other

Scientists in the U.S. have developed an algorithm that can predict the optimum method for transforming any cell type directly into any other specified cell type, without the need to generate induced pluripotent stem cells (iPSCs) as intermediates. The cell transformation algorithm is based on a mathematical control model, which the researchers have dubbed data-guided control (DGC) – and exploits the wealth of data that we already have on cellular activity, genome structure and gene expres