Algorithm Could Help Scientists Split a Protein and Reassemble It to Functionality

A team of biochemists and biophysicists reports that a computer-guided algorithm may help scientists find the right place to split a protein and then reassemble it to functionality. They add this could be another step toward using chemical and light signals to create new medical treatments and biosensors.The team published its study (“ Computational design of chemogenetic and optogenetic split proteins ”) in Nature Communications .“Controlling protein activity with chemoge