3D Bioscaffold Mimics Antigen-Presenting Cells for Improved T-Cell Expansion

Researchers in the U.S. have developed a 3D biomaterial scaffold that can promote much faster ex vivo expansion of functional T cells than currently available technologies. The new scaffold is designed to provide the cues that are delivered to T cells by the body’s own antigen-presenting cells (APCs), in context, and so better mimic in vivo signaling by APCs. Led by David Mooney, Ph.D., at Harvard's Wyss Institute for Biologically Inspired Engineering and John A. Paulson School of Engineer